Two-time Oscar® winner Robert De Niro teams up with Uma Thurman and Bill Murray in this wildly offbeat, adventure-filled love story that proves when trouble comes, anything goes. When shy, soft-spoken Chicago detective Wayne "Mad Dog" Dobie (De Niro) inadvertently saves the life of local gangster Frank Milo (Murray), he's the reluctant recipient of an unusual one week "thank-you" gift - a beautiful bartender named Glory (Thurman)! Before the week is out, the two have fallen madly in love, making for a murderous showdown with Milo. Now Dobie must live up to his ironic nickname or it will be "no guts, no Glory" in this heartwarming comedy.